Saikat Chakrabarti made his fortune in tech. Now he wants to ban the data centers that power AI in San Francisco, the most important growth industry in the city and the engine of downtown's recovery.
That's not regulation. It's a kill switch. It kills SF jobs, guts the tax base, and hands the AI race to China.
A self-funded centi-millionaire with no SF roots, tech wealth making sure nobody else can get it, pulling up the ladder, not representing the desires of San Franciscans.
Under no circumstances can he be elected to Congress.
10 years since AlphaGo
Incredible
Demis Hassabis: It was a huge honour to meet with President @Jaemyung_Lee in Seoul. Deeply appreciate and impressed by our thoughtful exchange about AI safety and the importance of using AI to advance science. Korea has a leading part to play in that, and we look forward to working together!
a great codex tutorial:
Riley Brown: Learn 95% of Codex in 28 minutes
These are the 7 knowledge work capabilities...
inside Codex, the super-app
00:00 Intro
02:19 Capability 1 - Full File Access
07:41 Capability 2 - Persistent Memory
10:46 Capability 3 - Plugins
13:52 Capability 4 - Skills
19:22 Capability 5 -
a great codex tutorial:
Riley Brown: Learn 95% of Codex in 28 minutes
These are the 7 knowledge work capabilities...
inside Codex, the super-app
00:00 Intro
02:19 Capability 1 - Full File Access
07:41 Capability 2 - Persistent Memory
10:46 Capability 3 - Plugins
13:52 Capability 4 - Skills
19:22 Capability 5 -
Kaï Whitaker
Peter has had some awesome podcast episodes lately. A lot of insight into creative and progressive ways people are building with AI.
Peter Yang: "I shipped 9 failed products before one took off...now I'm doing $1M+/month."
Here's my new episode with @tibo_maker, a solo founder who bootstrapped 5 AI products to $1M+ / month.
Tibo walked me through his exact playbook:
✅ How to validate ideas and fail fast
✅ Why his top
Raphael Schaad
MIT student asked a question earlier today that a lot of young founders are quietly wondering about:
"Won’t the frontier labs just do everything?"
Yes it's true that OAI/Ant are shipping at incredible pace, but it's quite easy to avoid their blast radius and build amazing startups:
OpenAI is not going to build a cattle-herding drone, buy an old F-150 and drive from ranch to ranch like the founder of one of the fastest-growing YC W26 startups, Graze Mate.
Anthropic is not going to integrate with dental insurance verification systems (Lance).
Google is not going to navigate NATO procurement (Milliray).
The value is in the last mile, not the model. Sales cycles require humans who understand the customer. And most importantly, the market is expanding, not shrinking: AI isn't cannibalizing the existing 1% software spend — it's unlocking the other 5-6% that was going to humans. That's a much bigger market for startups yet-to-be-founded than the one the labs are playing in.
Now, what DOES seem risky?
A thin UI layer on top of ChatGPT with no domain expertise; a general-purpose chatbot or assistant; or a product that gets obsolete when model capabilities improve.
But — tools for specific industries; "full-stack" AI companies that actually are the service (AI law firm, AI accounting firm, AI uranium exploration company); or generally products where the customer doesn't want a tool but an outcome — are defensible ideas for startups.
kind of hilarious this works
I have alot of respect for solo AI builders.
The world is their playground now.
Peter Yang
This is actually brilliant for personal agents @Shpigford - stealing this for my OpenClaw now.
This is actually brilliant for personal agents @Shpigford - stealing this for my OpenClaw now.
If you’re sick of hearing about agents 2026 is going to be the eternal September for you
guglielmo: Hot take: Hermes Agent is better than Clay (at enrichment)
I pass websites email leads to Clay, and lots of time no results. So I got Hermes agent to do a second pass.
Have been getting SUCH good results with the Browser Harness (@browser_use) + Hermes Agent.
Another day,
Sgt Sref
Can AI Dance? 🕺
Testing @Replit for slide creation
Replit ⠕: You're going to be embarrassed by the slides you made before AI
Meet Replit Slides
The first AI slides with stunning design
Vox
found a skill combo that works in both codex and claude code: /ce-ideate (from Every's compound-engineering) + gstack-design-consultation (from Garry Tan's gstack), running together. great way to build a new feature.
example: building a sticker chart app for my kid. sweep her room, earn a star. ten stars trade for a real reward.
/ce-ideate lists 30 directions, kills 25, keeps 5 worth shipping with reasons why each survived (does the parent phone show progress? do we add a leaderboard?). gstack-design-consultation runs in parallel, brings a designer's eye into the loop.
after both finish, i'd chain /ce-plan or gstack's /plan-eng-review to turn it into an execution plan with a task list. drop the execute command into codex's queue, queue a /review behind it. want to audit the design too? /design-review runs alongside /review in parallel.
then go grab food or take a walk. come back, PR is sitting there ready to merge.
ideate + design → plan → execute → review. and honestly you can queue the whole chain if you're being lazy lol.
James Pethokoukis ⏩️⤴️
"A decade ago, AI was supposed to replace radiologists. Today, radiologists make more than $500,000 per year, and their employment continues to grow, see chart below. Reading scans is a task, not a job, and when the task gets cheaper, demand for the job grows."
Paul Graham
Just went to visit Legora. Most impressive startup I've been to visit in years. They're going to surpass Harvey in 2027. After that their only potential rivals will be the model companies. And if ever there was a territory you could defend against the model companies, law is it.
GPU library performance can be very notchy -- runtime of batched torch.linalg.solve_ex() went up by over 10x going from 511x511 matrices to 512x512.
Greg Brockman
terminal has been my primary interface to my computer for almost two decades. now it’s the Codex app.
Yam Peleg: I was not expecting the Codex App to be even better than using the terminal.
Highly recommend everyone to try.
If you are on Linux just tell GPT-5.5-xhigh to “find a way to get it, it’s known to be easy”
terminal has been my primary interface to my computer for almost two decades. now it’s the Codex app.
Yam Peleg: I was not expecting the Codex App to be even better than using the terminal.
Highly recommend everyone to try.
If you are on Linux just tell GPT-5.5-xhigh to “find a way to get it, it’s known to be easy”
terminal has been my primary interface to my computer for almost two decades. now it’s the Codex app.
Yam Peleg: I was not expecting the Codex App to be even better than using the terminal.
Highly recommend everyone to try.
If you are on Linux just tell GPT-5.5-xhigh to “find a way to get it, it’s known to be easy”
Cool to see it is useful in other areas
Jon Tucker: Adapted @garrytan gstack methodolgy to non coding work in our company harness. It's the missing link I've been looking for to add enough structure for us as humans to work at the level of this AI OS for our company that we built,
OpenSource+AI=amazing. Was FAST to integrate.
The brain's sample efficiency doesn't come from architecture. It comes from loss functions.
Subcortical structures encode rich evaluation signals that make learning more efficient than raw gradient descent on weights.
Same thing could be true for AI agents. Experimenting now with GStack /review: Could a coding agent with fat, multi-axis evaluation skills (not just pass/fail) converge faster than one backed by a better model with thin feedback?
Can a fat skill compete with terabytes of training data? Many would say no, but how crazy would it be if that answer were yes?
Dwarkesh Patel: There's a quadrillion-dollar question at the heart of AI: Why are humans so much more sample efficient compared to LLM? There are three possible answers:
1. Architecture and hyperparameters (aka transformer vs whatever ‘algo’ cortical columns are implementing)
2. Learning rule
Y Combinator
Demis Hassabis (@demishassabis) has had one of the most extraordinary careers in tech.
He started as a chess prodigy and video game designer at 17 before getting a PhD in neuroscience and going on to found DeepMind. His lab cracked Go, solved protein structure prediction with AlphaFold, and then gave it away free to every scientist on earth. That work won him the 2024 Nobel Prize in Chemistry. Today he leads @GoogleDeepMind, pushing toward the same goal he set as a teenager: AGI.
On this special live episode of How to Build the Future, he sat down with YC's @garrytan to talk about what still needs to happen to get us to AGI, his advice for founders on how to stay ahead of the curve, and what the next big scientific breakthroughs might be.
01:48 — What’s Missing Before We Get To AGI?
03:36 — Why Memory Is Still Unsolved
06:14 — How AlphaGo Shaped Gemini
08:06 — Why Smaller Models Are Getting So Powerful
10:46 — The 1000x Engineer
12:40 — Continual Learning and the Future of Agents
13:32 — Why AI Still Fails at Basic Reasoning
15:33 — Are Agents Overhyped or Just Getting Started?
18:31 — Can AI Become Truly Creative?
20:26 — Open Models, Gemma, and Local AI
22:26 — Why Gemini Was Built Multimodal
24:08 — What Happens When Inference Gets Cheap?
25:24 — From AlphaFold to the Virtual Cells
28:24 — AI as the Ultimate Tool for Science
30:43 — Advice for Founders
33:30 — The AlphaFold Breakthrough Pattern
35:20 — Can AI Make Real Scientific Discoveries?
37:59 — What to Build Before AGI Arrives
i love that the team does stuff like this
Mugilan S: Codex is not like claude code.
if you know the limit is going to end, like last 10 to 8%, give an very long run task, and even after the limit got ever, it will continue to do the task until the task was completed.
Shout out to @OpenAI team.
Peter Yang
OpenAI vs. Anthropic gets all the attention, but @GoogleLabs is quietly shipping some of the most interesting AI products right now.
I made a 16-min video showing you what 5 Labs products are capable of:
1. Pomelli for marketing
2. Stitch for design
3. Genie for 3D worlds
4. Flow for videos
5. NotebookLM for synthesis
📌 Watch now: https://youtu.be/BQ_mgojj0Mo
Don't know what's going on with @claudeai but I find that I often now have to wait 3-5 seconds randomly for it to respond just using the basic web UI.
San Francisco Unified School District is laying off real teachers to prioritize paying 6 figure sums to buy worthless PowerPoints that don't help the kids of San Francisco, and people should know this and vote accordingly
Liz4SF: 🚨Friends of Lowell issues a Demand Letter to sfusd under Brown Act for illegal mandate of “Voices” ethnic studies. They sued in 2021 & won over similar violations w/ removal of merit from Lowell. All BOE except Supriya voted $7.3M for 2 semester unvetted “Voices”. Once again,
RJ Honicky
Noetik’s AI value proposition: “cohort selection”
“When I do my drug’s clinical trials, who should participate?”
Obviously, if you get that wrong, then your drug won’t “work,” even if it actually works!
Ron Alfa explained to us how they do this using cheap imaging
1/
Re "That's not skepticism. That's cope."
yeah yeah, my claw wrote that for me, I didn't catch it when I pasted it, sorry
I already /skillified it so that it wouldn't do that anymore ok
AI Engineer
Full Workshop: @OpenAI Codex masterclass
The agent is no longer just one chat window. In this workshop, @reach_vb and @kagigz get into how coding systems start to change when you can delegate work across subagents, split tasks up, and manage more context than a single thread can comfortably hold.
If you're trying to understand where the next generation of coding agents is going, this is a useful look at the shape of that future from inside @OpenAI!
Full Workshop: https://youtube.com/watch?v=MhHEGMFCEB0
Vaibhav (VB) Srivastav: http://x.com/i/article/2033608358494617600
Erik Thorelli
i miss @AIEMiami already
World Labs
Expand is now available to everyone!
Extend your world in any direction you choose: around corners, into rooms, and beyond what you can see 👀
Replit ⠕
Building apps is easy- keeping them running isn’t
Introducing Replit Application Monitoring
Replit Agent now watches your app in production, investigates issues, and helps fix them- so you don’t have to
Filip Kozera
Proactive agent that thinks and acts like you.
Multiplayer AI Brain for teams.
Proper GUI for commanding 50 agents.
http://Sauna.ai is all three. Sauna goes live today. First 2000 people, use access code LAUNCH for $80 of weekly(!) credits.
Let’s explain. Multiplayer only works once the personal brain is powerful. So let's start here.
Personal AI Brain
3,800+ tools connected. State of the Art memory. Skills and schedules you teach once that get repeated forever on cheaper models. An AI first CRM.
Lives on the cloud so you can initiate tasks from anywhere: iMessage, Slack, Email. Also no need for a Mac mini 😉
GUI
AI agents have been stuck in their MS-DOS era. A chat box, a scroll buffer, no way to command 50 of them. We built the first GUI: Live sessions on one side, work waiting for your sign-off on the other, plus the things Sauna kicked off while you were asleep waiting for review. Game mode helps clear the queue with actual joy.
Okay so far so good, but how to give benefit of what you built to more people or whole team?
Multiplayer
Once your Sauna actually knows you and you gave her access to your tools, you can use multiplayer.
Two modes:
- Brain access. My co-founder Robert plugged my brain as a tool into his Sauna last month. He can ask it about pricing while I'm in other meetings, gets a sourced answer back, never has to interrupt me. That’s read only. Yolo mode gives him access to all my tools too :O
- Communal Saunas extend that to whole companies with proper permissioning. Folder owners decide what's true for the whole company and build skills. Most get their personal brain + read access to communal files and memories. Works also for group planning my best friend's bachelor party.
The Way
I’ve been obsessed about AI Brain since 2016. Our human brains suck at some things like memory and are brilliant at others like creativity. We are also particularly bad at thinking we are all on the same page and then realising weeks later that we weren’t. Most leaders spend their days being the human diff tool, catching contradictions in hallway conversations and Slack threads. Repeating themselves 50 times. Now every company is spinning up hundreds or thousands of agents that drift faster than humans do, feeding each other their drift as context. Compounding rot.
After 10 years and one failed company in this space we are launching the solution.
The Launch
We thought about a celebrity launch. Margot Robbie in a bathtub explaining agents. But then we realised the same money gives the first 2,000 people free daily credits, every day, until we burn through that $1,000,000.
Sauna runs Claude, GPT-5, Gemini, GLM-5.1, DeepSeek, Kimi so you can budget yourself. The labs are racing to lock you so they can milk you in a year. We picked your side.
Onboarding
It’s live at http://app.sauna.ai We’ve preheated saunas based on a niche. Use the access codes in the comments to get a better experience.
“Yeah agents can help you build apps, but who maintains them?”
Also agents:
Replit ⠕: Building apps is easy- keeping them running isn’t
Introducing Replit Application Monitoring
Replit Agent now watches your app in production, investigates issues, and helps fix them- so you don’t have to
Zhen Li
Pitching deck for investors under $1.3
Magomed Kurbaitaev: I swear I spent over $10,000 on pitch decks when I started Gameplan.
Agencies, designers, revisions, back-and-forth, more revisions and “final_final_v7.pdf”.
Replit just built an investor deck in 4 minutes for $1.23
I am still processing this. Insane.
Dwarkesh Patel
Did a very different format with @reinerpope – a blackboard lecture where he walks through how frontier LLMs are trained and served.
It's shocking how much you can deduce about what the labs are doing from a handful of equations, public API prices, and some chalk.
It’s a bit technical, but I encourage you to hang in there - it’s really worth it.
There are less than a handful of people who understand the full stack of AI, from chip design to model architecture, as well as Reiner. It was a real delight to learn from him.
Recommend watching this one on YouTube so you can see the chalkboard.
0:00:00 – How batch size affects token cost and speed
0:31:59 – How MoE models are laid out across GPU racks
0:47:02 – How pipeline parallelism spreads model layers across racks
1:03:27 – Why Ilya said, “As we now know, pipelining is not wise.”
1:18:49 – Because of RL, models may be 100x over-trained beyond Chinchilla-optimal
1:32:52 – Deducing long context memory costs from API pricing
2:03:52 – Convergent evolution between neural nets and cryptography
The Economist
Democrats could try picking a young candidate who has a solid record of running a big city https://www.economist.com/united-states/2026/04/29/a-radical-idea-for-governing-california?taid=69f249c405fd1e0001605013&utm_campaign=trueanthem&utm_medium=social&utm_source=twitter
New @BeatSaber music pack is out, and I must be one of the first to play, landing a top-10 score that will surely be out of the top 100 by tomorrow.
Made with Replit Slides.
Sgt Sref: Can AI Dance? 🕺
Testing @Replit for slide creation
TheUnsaid
Re There are so many shady, suspicious things about the ethnic studies program:
1) SFUSD mandated it to be 2 semesters, but CA law only requires 1 semester. That other semester takes away additional instruction in math, english, science, etc..
2) Parents can't preview the content in "Voices An Ethnic Studies Survey". Why keep it secret? They say it's for copyright reasons, but even Amazon often allows users to preview many pages of a book online before buying. That especially should be important for parents concerned for their children.
3) the company that publishes the book also hides who is behind it. Their website & "about" section isn't even transparent enough, to show a single person's name. https://gibbssmitheducation.com/about That's unusual for a company website, and it should be doubly so for a company that serves children.
4) People commonly know what to expect with other classes: Geometry, World History, Social Studies -- what's inside is generally standard. But "ethnic studies?" It's more of a mystery. It's a recently made up subject for high school. And it is highly prone to politically biased & manipulative content.
Too much secrecy & hiding. Too much rushing through.
Overall, way too SHADY.
Set your calendars like @aroogle did
Replit ⠕: Free Agent usage starts at 5:00am PST on May 2 for 24 hours
Kenneth Roth
This is what an impending midterm disaster looks like for Republicans. https://trib.al/eLV1GmR
Mikhail Parakhin
I mentioned Liquid AI to @swyx - and he immediately got Maxime to discuss their approach to training. Worth a listen.
swyx 🇸🇬: @MParakhin @ilyasut and first AIE x @liquidai talk is live!
https://x.com/aiDotEngineer/status/2049458425059537025
SFUSD paid $147K for an "independent" review of its ethnic studies curriculum that was stacked with insiders, had no passing threshold, and silenced critics. The Board voted to approve it anyway.
Litigation incoming.
https://gli.st/adput2zf
Noah Smith 🐇🇺🇸🇺🇦🇹🇼
Seems illegal
Also this is why people hate progressivism
Aaron Sibarium: NEW: Blue jurisdictions are rationing homeless services based on race.
In Portland, a non-white, non-native English speaker who is LGBT would get priority over a domestic violence survivor with a 6 yr old child who's been homeless for 12+ months.
The policies are shocking.🧵
Join the YC Paper Club
Y Combinator: This summer we're launching YC Paper Club to bring researchers & builders together.
Every few weeks we'll host a small group dinner in Mountain View to share and discuss new research papers.
Interested in both research & building the future? Sign up at: https://events.ycombinator.com/ycpaperclub
HappyHorse 1.0 feels benchmaxxed…
Seedance is beating it (subjectively) in every single test I’ve run so far
Ahmad Hajj
Re 6/ Most "AI for business" companies right now are still operating at Layer 1 with prettier UIs.
The interesting work this year is Layer 3.
@garrytan keeps pointing at the right shape with GBrain and GStack. The companies that figure out how to compile a brain — not just index one — own the next category.
Captain Mark Kelly
Science is how we’ve cured diseases and how we just sent four humans around the Moon. It’s a big reason why we’re the greatest country on Earth, but firing the National Science Board shows just how much Trump doesn’t understand that.
Free accounts for teachers, 50% off for students!
Replit ⠕: The classroom changed. The homework changed. How we learn changed.
18 million students already build on Replit and now, there's a dedicated space just for them. No setup. No lectures. Just building.
Teachers get free access. Students get 50% off Core. And if you're running a
Matias 🧉
Re @vercel Ship26 is live!
This year, we shipped a 3D device that can create WASM apps using wterm, just-bash, and @workflowsdk
...and a landing full of agents that walk around the site using a dynamic navigation mesh.
Greg_Ld
Thanks @mattshumer_ for finding one more gem use-case for the incredible GPT-Image-2. You can generate stop motion videos just by asking !
https://x.com/mattshumer_/status/2049583863576617223?s=20
Matt Shumer: GPT-Image-2 can be a video-gen model if you want it to be!
Just ask ChatGPT to generate stop motion video, frame-by-frame.
It works shockingly well and is super controllable!
build your own agents with codex app-server
CHOI: The Codex App Server is massively underrated.
You can inject Codex-level intelligence into any platform using your ChatGPT account.
I embedded it into Chrome… and it works flawlessly.
And yes… it’s 100% open source.
https://github.com/GENEXIS-AI/chromex
build your own agents with codex app-server
CHOI: The Codex App Server is massively underrated.
You can inject Codex-level intelligence into any platform using your ChatGPT account.
I embedded it into Chrome… and it works flawlessly.
And yes… it’s 100% open source.
https://github.com/GENEXIS-AI/chromex
I’ve been very pleasantly surprised by how useful GPT Image 2 is for app building:
Romain Huet: GPT-5.5 + GPT-Image-2 is becoming one of the best combos for building apps!
@dkundel breaks down why it works so well. We built those learnings into the Build Web Apps plugin, so Codex can handle the design-to-app loop for you. 👌
I’ve been very pleasantly surprised by how useful GPT Image 2 is for app building:
Romain Huet: GPT-5.5 + GPT-Image-2 is becoming one of the best combos for building apps!
@dkundel breaks down why it works so well. We built those learnings into the Build Web Apps plugin, so Codex can handle the design-to-app loop for you. 👌
Brivael
Un truc qui m'a marqué en arrivant à YC.
Premier meeting, @garrytan nous dit : "dans cette pièce, 10% d'entre vous vont potentiellement devenir milliardaires. Faites-vous des potes avec tout le monde. Parce que même si votre boîte ne marche pas, vous allez pouvoir vous entraider toute votre vie."
Et c'est exactement ce qui se passe. Il y a une bienveillance vraiment rafraîchissante dans cet écosystème. Personne ne te regarde de travers parce que tu vises trop haut. Au contraire, plus tu vises haut, plus les gens veulent t'aider.
C'est ça qui manque cruellement à la France.
Le soutien à l'extrême ambition.
Tant que dire "je veux devenir milliardaire" sera un problème social en France, on n'avancera pas. Tant qu'on n'aura pas de bienveillance écosystémique sur ces sujets là, on stagnera.
Le blocage français n'est plus technique, ni même réglementaire au premier ordre. Il est culturel. C'est un blocage sur la création de valeur elle-même. On a intériorisé l'idée que la richesse est suspecte, que l'ambition est vulgaire, que viser grand c'est trahir une forme d'humilité républicaine.
Pendant ce temps, on rentre dans une décennie d'abondance extrême. L'IA, l'énergie, la robotique, la biotech. Les ordres de grandeur de création de valeur vont être historiques. Et la question n'est pas de savoir si ça va arriver, c'est de savoir qui va capter cette valeur.
Si on continue à punir socialement ceux qui essayent, on regardera les autres le faire. Encore.
On a un vrai travail collectif à faire en tant que français. Réapprendre à célébrer ceux qui construisent. Arrêter de confondre ambition et arrogance. Comprendre qu'un écosystème où les gens s'entraident à viser haut produit plus de réussites pour tout le monde, pas moins.
La bienveillance envers l'ambition n'est pas naïve. C'est stratégique.
Republicans against Trump
Trump’s FCC chair, Brendan Carr, says he plans to punish and potentially revoke broadcast licenses for TV networks critical of the Trump administration:
“I’d be surprised if we don’t go down the path of license revocation for some. It will be up to them and their conduct.”
This is fascism. This is what they do in authoritarian countries.
This is cancel culture on steroids.
Where’s the outrage?
Now everyone can experience getting paged at dinner because the site is down 😅